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Indicated for the treatment of candidiasis, fungal skin infections. It is also given for systemic infections including systemic candidiasis, coccidioidomycosis and cryptococcosis, and has been tried in blastomycosis, histoplasmosis and sporotrichosis.
Place of Origin
Philippines
Product Usage
Adults
For systemic candidiasis: take 400 mg on Day 1, followed by 200 mg daily for 28 days.
For cryptococcal meningitis: take 400 mg for acute and 200 mg for relapse on Day 1, followed by 200 mg daily. Duration of therapy is 10 - 12 weeks after CSF culture becomes negative.
For superficial mucosal candidiasis: usual dose is 50mg daily, 100mg daily may be given if necessary. Treatment usually continues for 7 to 14 days in oropharyngeal candidiasis (except in severely immunocompromised patients), for 14 days in atrophic oral candidiasis associated with dentures, and for 14 to 30 days in other mucosal candidal infections including esophagitis.
For vaginal candidiasis: 150mg by mouth as a single dose For dermatophytosis, pityriasis versicolor, and Candida infections: 50mg daily for up to 6 weeks.
For immunocompromised patients at risk of fungal infections: a prophylactic dose of 50 to 400mg daily. Children Over 4 weeks of age: 3mg/kg daily for superficial infections (a loading dose of 6mg/kg may be used on the first day if necessary), and 6 to 12mg/kg daily for systemic infections.
For prophylaxis in immunocompromised children: 3 to 12mg/kg daily. For infants under 2 weeks of age: all these doses should be given once every 72 hours. Aged between 2 and 4 weeks: the doses should be given every 48 hours.
Ingredients
Fluconazole
Warnings
Fluconazole should be used with caution in patients with impaired hepatic or renal function. Abnormalities in haematological
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