Pantoprazole Ec 40 mg 1 Tablet [Prescription Required]

Pantoprazole is proton pump inhibitor with actions and uses similar to those of omeprazole. It is given as sodium salt but doses are expressed in terms of the base. Pantopazole sodium 11.28 mg is equivalent to about 10 mg of pantoprazole. Once-daily doses should be taken in the morning in the treatment of:
·, , , , , , , , , Gastro-oesophageal reflux disease

·, , , , , , , , , Peptic ulcer disease

·, , , , , , , , , Prophylaxis for NSAID-associated ulceration

·, , , ,In the treatment of pathological hypersecretory states such as the Zollinger-

Place of Origin

Korea

Product Usage

In the treatment of gastro-oesophageal reflux disease, the usual oral dose is 20 to 40 mg once daily for 4 weeks, increased to 8 weeks if necessary. For maintenance therapy, treatment can be continued with 20 to 40 mg daily. Alternatively, for recurring symptoms, an on-demand regimen of 20 mg daily may be given.

The usual dose for the treatment of peptic ulcer disease is 40 mg once daily. Treatment is usually given for 2 to 4 weeks for duodenal ulceration, or 4 to 8 weeks for benign gastric ulceration. For the eradication of Helicobacter pylori, pantoprazole may be combined with two antibacterial medications in a 1-week triple therapy regimen. Effective regimens include: pantoprazole 40 mg twice daily combined with clarithromycin 500 mg twice daily and amoxicillin 1 g twice daily, or combined with clarithromycin 500 mg twice daily and amoxicillin 1 g twice daily, or combined with clarithromycin 250 mg twice daily and metronidazole 400 mg twice daily.

Patients who require prophylaxis for NSAID-associated ulceration may take 20 mg daily.

In the treatment of pathological hypersecretory states such as the Zollinger-Ellison syndrome, the initial dose is 80 mg daily, adjusted as required. Doses of up to 240 mg daily have been used. Daily doses greater than 80 mg should be given in 2 divided doses.

Ingredients

Pantoprazole (as sodium sesquihydrate)

Warnings

Dosage may need to be reduced in severe hepatic impairment. Liver function should be monitored regularly. Therapy should be stopped if liver enzymes are elevated.

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