Sacubitril Valsartan 100mg 1 Tablet [Prescription Required]

REMINDER: A doctor&rsquo,s prescription is required to purchase this product. To avoid delay in delivery or cancellation of your order ,(before the item is SHIPPED), please email a copy of your prescription (.jpeg or .pdf file format) to ,OnlinePharmacy@watsons.com.ph ,with your order number after Checkout. Our pharmacist will also get in touch with you to validate your prescription. Please be ready to show your original prescription upon claiming/delivery of your order.

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Reduce the risk of CV mortality &, morbidity in adult patients with systolic heart failure (NYHA class II-IV, LVEF &le,40%). In combination with other heart failure therapies (eg, &beta,-blockers, diuretics &, mineralocorticoid antagonists) as appropriate in place of an ACE inhibitor or angiotensin II receptor blocker (ARB).

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Contraindications:
Hypersensitivity to sacubitril or valsartan. Concomitant use with ACE inhibitors. History of angioedema related to previous ACE inhibitor or ARB therapy. Hereditary or idiopathic angioedema. Aliskiren-containing medicinal products in patients with DM or renal impairment (eGFR <,60 mL/min/1.73 m2). Severe hepatic impairment, biliary cirrhosis &, cholestasis. Pregnancy (2nd &, 3rd trimester).

Place of Origin

Singapore

Product Usage

Starting dose: 100 mg bid. Double the dose at 2-4 wk to the target dose of 200 mg bid as tolerated by the patient. Patient not currently taking an ACE inhibitor or an ARB Start at 50 mg bid & slow dose titration (doubling every 3-4 wk). Patient with systolic BP ≥100-110 mmHg, moderate (eGFR 30-60 mL/min/1.73 m2) & severe (eGFR <30 mL/min/1.73 m2) renal impairment, moderate hepatic impairment (Child-Pugh B) Starting dose: 50 mg bid.

Ingredients

Per 50 mg FC tab Sacubitril 24.3 mg, valsartan 25.7 mg. Per 100 mg FC tab Sacubitril 48.6 mg, valsartan 51.4 mg. Per 200 mg FC tab Sacubitril 97.2 mg, valsartan 102.8 mg

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