Tranexamic Acid Film-Coated Table 500mg [PRESCRIPTION REQUIRED]
TRANSTAT Tranexamic Acid Film-Coated Table 500mg [PRESCRIPTION REQUIRED]
INDICATIONS Short-term use for haemorrhage or risk of haemorrhage in increased fibrinolysis or fibrinogenolysis. Local fibrinolysis as occurs in the following conditions:
- Prostatectomy and bladder surgery
- Menorrhagia
- Epistaxis
- Conisation of the cervix
- Traumatic hyphaema
- Hereditary angioneurotic oedema
- Management of dental extraction in haemophiliacs
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Place of Origin
India
Product Usage
DOSAGE AND MODE OF ADMINISTRATION
1) Local fibrinolysis: The recommended standard dosage is 15-25 mg/kg bodyweight (i.e. 2-3 tablets) two to three times daily. For the indications listed below the following doses may be used:
a) Prostatectomy: Prophylaxis and treatment of haemorrhage in high risk patients should commence pre- or post-operatively; thereafter
2 tablets three to four times daily until macroscopic haematuria is no longer present.
b) Menorrhagia: Recommended dosage is 2 tablets 3 times daily as long as needed for up to 4 days. If very heavy menstrual bleeding,
dosage may be increased. A total dose of 4 g daily (8 tablets) should not be exceeded. Treatment with Tranexamic Acid (Transtat®)
Film-coated tablets should not be initiated until menstrual bleeding has started.
c) Epistaxis: Where recurrent bleeding is anticipated oral therapy (2 tablets three times daily) should be administered for 7 days.
d) Conisation of the cervix: 3 tablets three times daily.
e) Traumatic hyphaema: 2-3 tablets three times daily. The dose is based on 25 mg/kg three times a day.
2) Hereditary angioneurotic oedema: Some patients are aware of the onset of the illness; suitable treatment for these patients is intermittently
2-3 tablets two to three times daily for some days. Other patients are treated continuously at this dosage.
3) Haemophilia: In the management of dental extractions 2-3 tablets every eight hours. The dose is based on 25 mg/kg.
Renal insufficiency: By extrapolation from clearance data relating to the intravenous dosage form, the following reduction in the oral dosage is recommended for patients with mild to moderate renal insufficiency.
Serum Creatinine (?mol/l) : Dose tranexamic acid 120-249 : 15 mg/kg body weight twice daily
250-500 : 15 mg/kg body weight/day
Children's dosage: This should be calculated according to body weight at 25 mg/kg per dose. However, data on efficacy, posology and safety for these indications are limited.
Elderly patients: No reduction in dosage is necessary unless there is evidence of renal failure.Method of administration: Oral
Ingredients
"
Each film-coated tablet contains: Tranexamic acid, BP ………… 500 mg
Width
4.5
Height
6
Depth
12.5